Current Issue's

Feature Articles

Jun - Jul 2018

PI: The Road to Diagnosis and Treatment

"THE ROAD LESS traveled is frequently the more difficult path" is an adage that is particularly true for individuals with a primary immunodeficiency disease (PI), whose path to a correct diagnosis and treatment often takes years. And, while the delay in diagnosis has been significantly decreased today, taking between five and seven years, this isn't true for all. Some PI patients still aren't correctly diagnosed for more than a decade,1 leading to lifelong physical, mental and financial complications for patients and their families... full article

PI and Women's Health: Pregnancy and Beyond

Primary Immunodeficiency diseases (PIs) encompass a large number of diverse immune disorders. A common feature many PI patients share is their age of diagnosis, often approaching or in the midst of childbearing years. Since a delay in diagnosis of many years and even decades is not uncommon in milder forms of PI, many patients struggle with raising families while in poor health... full article

PI and Allergies

Having a primary immunodeficiency disease (PI) and allergies can seem illogical since PI is caused by a weakened or compromised immune system whereas allergies are the result of an overactive immune system. But, according to Roger Kobayashi, MD, an allergist-immunologist in Omaha, Neb., the seeming contradiction is based on an outdated understanding of what constitutes a compromised immune system. "The old concept that all these immune abnormalities were separate has been reanalyzed and changed," he explained... full article

Confronting the Causes and Complications of Kawasaki Disease

KawasaKi disease (Kd) was first described by Japanese pediatrician Tomisaku Kawasaki in 1967. His report identified the disease in 50 infants suffering from persistent fever, rash, lymphadenopathy (abnormal size lymph nodes), edema, conjunctival injection (redness in the white sclera of the eye), redness and cracking of the lips, strawberry tongue (a swollen, bumpy tongue) and convalescent desquamation (shedding of the outermost membrane or layer of a tissue such as skin). KD is also a leading cause of acquired heart disease in the U.S... full article